A goalless draw at the Etihad Stadium was enough to secure passage to the last eight, which had been all but guaranteed following a comprehensive 5-0 first leg win over the Portuguese champions in Lisbon.
Youngsters CJ Egan-Riley, James McAtee and Luke Mbete were all handed their senior European debuts by Pep Guardiola, while goalkeeper Scott Carson was also brought on for his first Champions League appearance since 2005.
And Carson was called into action soon after, making a crucial save to deny Paulinho from close-range.
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