Pep Guardiola’s side secured a place in the fifth round of the FA Cup with a win away in East London.
The League One side were looking to pull off a cup shock and took an early lead when Jamie Donley’s long-range strike hit the crossbar and rebounded in off Stefan Ortega Moreno.
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City fought back after the break with Rico Lewis’s strike deflecting in off Abdukodir Khusanov before substitute Kevin De Bruyne grabbed the winner from Jack Grealish’s throughball.
It was a cup tie that summed the magic of the competition with Orient giving everything to try to pull off a giantkilling.
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