Sunday’s game at the Etihad Stadium will be our third clash this season against the London Club with another Premier League game at home in May to come.
Riyad Mahrez’s second half winner secured a 1-0 victory in the Premier League on Thursday to follow on from our 2-0 win in the Carabao Cup in November.
Graham Potter’s side are suffering from several injuries with Raheem Sterling and Christian Pulisic both substituted early in their midweek defeat at Stamford Bridge.
But Guardiola expects the Chelsea boss to regroup for the third round clash and is happy to be back at the Etihad for the fixture.
“It’s better for us to face Chelsea at home with our fans after a victory - that’s much better definitely,” he said.
“It could be a very different game, maybe Graham changes the shape, I don’t know. I know they struggled with injuries with two or three important players. Jorginho wasn’t there, Mason Mount wasn’t there, I don’t know the reason why.
“We were able to win four Carabao Cups in a row because every competition is important.
“Of course [the FA Cup] is important but now it’s rest, recovery and prepare with the fresh legs for this game.”
