The Belgian becomes just the 18th man in our Club’s history to reach three figures for goals scored.
Jean-Philippe Mateta put the hosts ahead early on, before De Bruyne blasted us level.
Rico Lewis struck us ahead after the break, before Erling Haaland connected with De Bruyne‘s cross to make it 3-1.
The landmark goal arrived with 20 minutes left to play at Selhurst Park, with De Bruyne powering the ball into the net with his left foot from 18 yards.
“Yeah, it’s funny. I had a conversation with Erling [Haaland] and Phil [Foden] and said the only goal I want is to score 100 before you guys,” he said. “Erling was like 18 behind but he would probably score that in two games!
“It’s a proud moment. It means that I’ve had longevity here. It means a lot of good moments for this club.
“It’s been my home, hasn’t it? I’ve come when I was basically still a young kid. Now I’m an older man in this squad and I have three kids who grow up very quickly.
“I’ve had so many good moments with the team and we won many trophies and parades.
“It’s hard to put into context but I appreciate everything that has happened and I think the supporters and club do too.”
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The midfielder also spoke about his first goal of the afternoon being one of his best ever, reserved high praise for teenager Lewis and reflected on the team’s response to conceding the early goal.
Watch the entire interview via the video at the top of the page.