Back in October 2011, Roberto Mancini’s challengers ripped through Sir Alex Ferguson’s champions, scoring six as we set a marker for the title race to come.
It was the most emphatic City victory in the history of our rivalry and our biggest win at Old Trafford since 1955.
Mario Balotelli opened the scoring in the 22nd minute and it remained that way until half-time.
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The second came on the hour, again through Balotelli to open the floodgates. Sergio Aguero added a third shortly afterwards before United’s Darren Fletcher gave the hosts a glimmer of hope.
That was quickly extinguished with an Edin Dzeko brace either side of a David Silva finish to cap off an unforgettable day.
It would prove to be pivotal later in the season, as we lifted the Premier League title thanks to that iconic Aguero goal against QPR.
Relive our famous Old Trafford win via the video above...