City head to Merseyside on Sunday 10 March for a 15:45 (UK) kick-off as the top two teams face each other in a mouth-watering clash.
Both sides go into the game in good form with City winning 16 of our last 17 matches while Liverpool have won their last seven.
It will also see a clash of two in-form striker with Erling Haaland scoring eight goals in his last five appearances while Darwin Nunez has five in his last four matches.
When we met earlier this season at the Etihad, the game finished 1-1 with Trent Alexander-Arnold scoring a late equaliser after Haaland put us ahead.
It could also be the last-ever meeting between Guardiola and Jurgen Klopp after the Liverpool boss announced he was leaving at the end of the season.
During their time in England, the coaches have met 21 times, with City winning seven and Liverpool eight with six draws.
Check out the best stats from the encounter’s history in the video above…
LIVERPOOL V CITY COVERAGE
Our official app allows you to follow all of the action from Anfield in one place.
Minute-by-minute text updates will begin in our Matchday Centre two hours before kick-off, while our Matchday Live show will begin at 14:30 (UK).
We will have guests Izzy Christiansen and Joleon Lescott on the latest Matchday Live show, offering their expert insight before, during and after the action.
They will also answer viewer questions throughout the broadcast, with audience participation actively encouraged on Matchday Live. To get in touch, send a WhatsApp to: +447537186538.
During the game you can also listen to live audio commentary from Alistair Mann and Michael Brown while our text commentary continues.
Make sure to have push notifications turned on as well, so you can be alerted to key moments in the action, including goals, red cards and the team news.
You’ll be able to watch brief highlights from 19:30 (UK) with extended highlights – and a CITY+ full-match replay - following at midnight.