Los Blancos prevailed in 2021/22 with two late strikes after we had been in charge of the tie for much of the 180 minutes but we can put that behind us with victory in this campaign.
Both sides have won three of the previous eight meetings, with two matches ending in draws.
Pep Guardiola | We are not here for revenge
We have won three of the most recent four meetings between the sides but did lose the most recent, that bruising night at the Santiago Bernabeu last May.
Our rundown of the best goals we have scored against Real Madrid features a host of favourites from past and present. Kevin De Bruyne and Bernardo Silva make the list for their efforts last season, while Aleksandar Kolarov, Gabriel Jesus and Edin Dzeko are also involved.
Watch our favourites against Real Madrid above...
REAL MADRID V CITY
We will have full coverage of Tuesday’s match right here on the official Man City app.
Our Matchday Centre will be available from 18:00 (UK), providing you with live text updates before, during and after the game.
Our Matchday Live programme will begin shortly before team news arrives at 18:45 (UK).
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Host Natalie Pike will welcome Paul Dickov, Shaun Goater and Steph Houghton into the studio to provide you with a City-centric view on the events in Spain.
During the game, Alistair Mann and Michael Brown will guide you through proceedings with our radio commentary.
Highlights will be available at 23:00 (UK) on Wednesday and CITY+ subscribers can watch a full 90-minute replay from midnight.
And don’t forget, the best way to follow Manchester City is by downloading our official app!
And when you do, turn on notifications to get alerted as to when our Matchday Live show starts.
Download on your mobile phone or tablet via Apple’s App Store or Google Play store, or, if you already have the app, then simply visit the stores and update.