The comprehensive victory sent Gareth Taylor’s side through to the quarter-finals with an 8-0 aggregate victory.
Ellen White and Sam Mewis both scored a brace, with Caroline Weir netting the other as City completely outclassed the home side.
As was the case in the home leg, Taylor’s team came flying out of the blocks and White fired us into an eighth minute lead after good combination play with Lauren Hemp.
Weir then converted a penalty after Esme Morgan’s header was handballed before Hemp and White combined again for the latter to smash home a third before the break.
Mewis took centre stage in the second half, netting a crisp finish after a surging run and completing the scoring with a powerful effort from Chloe Kelly’s cross.
Match report: Fiorentina 0-5 City