Gareth Taylor‘s side welcome the European Champions to the Joie Stadium on Wednesday 9 October, with kick-off set for 20:00 (UK).
A sell-out crowd is expected for one of the most hotly anticipated encounters of matchweek one.
City come into the tie on the back of a five-match unbeaten run in all competitions, with our most recent triumph seeing us beat West Ham United 2-0 on Sunday.
CITY v SPURS | GET YOUR ETIHAD TICKETS
However, Barcelona travel to Manchester in equally impressive form, putting eight past Real Madrid at the weekend.
Everything points to a thrilling encounter, which sees Laia Aleixandri, Leila Ouahabi, Keira Walsh and Ellie Roebuck all potentially line up against their former Clubs on both sides of the coin.
And ahead of the clash, the City players will be put through their paces at the CFA in a final training session before the action.
Check out training via the video above...
City v Barcelona App coverage
The Official Man City App will have all bases of our meeting with Barcelona covered from one handy place.
Minute-by-minute text updates will begin in our Matchday Centre an hour and a half before kick-off and during the game you can also listen to live audio commentary while our text commentary continues.
Make sure to have push notifications turned on as well, so you can be alerted to key moments in the action, including goals, red cards and the team news.
A comprehensive match report, reaction from Taylor and players, highlights and a CITY+ full-match replay will be available following full-time.
