The Spain international is yet to start a game for City but his contribution from three substitute appearances for the Blues have been enough to see him pip stand-in skipper Yaya Toure for the first award of the season.
Negredo had a perfectly good goal ruled out against Newcastle on his debut, then scored powerful headers in the next two games against Cardiff and Hull City Tigers and with a bit more luck, could have had another goal in each game.
Yaya pushed Alvaro all the way and a late surge in voting saw him end just a few hundred votes behind with Jesus Navas coming third.
Alex Dibden is the winning entrant from the 3,102 people who voted and will present the award to Alvaro in person and Kilian Salgado is the overseas winner who will receive a personal video message.
Thanks to everyone who took time to vote.