The Argentinian will make his second successive appearance having played in the Capital One Cup first round against Everton in midweek.
City will still have to do without Wilfried Bony and Vincent Kompany, while Eliaquim Mangala is sidelined after he picked up a hamstring strain at Goodison Park.
Boss Manuel Pellegrini said: “Willy will play both Cups. For Joe it’s good to work one complete week because we are playing so many games.
“Mangala and Bony are both still injured. We will know more tomorrow.
“Vincent is progressing, it’s a muscle injury and we must not rush him.
“I think one of most important merits of this squad is to continue being in all the competitions with so many injuries.
“I hope in future we have the normal amount of players.”
Pellegrini dismissed the notion that an FA Cup tie would be treated any differently to any other competition and that the injury situation will not force the Club into transfer window activity.
“I repeat we are going to be focused game by game,” he reflected.
“For the moment we continue with the same squad. I trust in the players - in the first four months we could do it so we can again.
“The priority for my team is to try and win every game, it doesn’t matter which competition you are in.
“That gives you an ambitious mind and a winning mind.”
Pellegrini has selection issues defensively, but is buoyed by the return of Pablo Zabaleta from injury and Bacary Sagna’s versatility - the Chilean boss pointed out he can play at centre-back if required.
Pellegrini also had a special word of praise for birthday boy David Silva.
He enthused: “I think David demonstrates in every game how important he is. He is a different player, so technical, it’s a gift to see him play, I hope he continues.”
Aside from Saturday’s game, Pellegrini was quizzed on his thoughts on the prospect of more video technology coming into football.
The International Football Association Board - the game’s lawmaker - are considering introducing trials to use video technology on goals, red cards, penalties and cases of mistaken identity.
Pellegrini said: “I think it’s very important. I think if the decision is over something that’s a mistake, such a as a foul inside or outside the box, then okay. Other things (matters of interpretation) are more difficult.
“I think each manager could have one review per half,” he added when asked about which decisions could be challenged.
