David Silva, Raheem Sterling, John Stones, Pablo Zabaleta and goalkeeper Claudio Bravo returned to the starting XI as the Blues aim to book a place at Wembley.
Team
City XI: Bravo, Zabaleta (C), Sterling, Agüero , De Bruyne, Sané, Silva, Clichy, Stones, Otamendi, Toure
Subs: Caballero, Fernando, Nolito, Kolarov, Delph, Fernandinho, Iheanacho
Tactics
Bravo, Zabaleta and Stones should come in as direct replacements for Willy Caballero, Bacary Sagna and Aleks Kolarov respectively at the back.
In midfield, Fernandinho dropping to the bench means Yaya Toure is likely to assume the holding midfield role.
With winger Raheem Sterling restored to the side, he should take up duties on the right flank, opposite Leroy Sane on the other side, but they could well switch depending on the pattern of play.
Creative midfielders David Silva and Kevin De Bruyne will be charged with providing striker Sergio Aguero with the ammunition up front.
Boro: Guzan, Barragan, Bernardo, Gibson, Fabio, Clayton, Leadbitter, De Roon, Stuani, Traore, Gestede
Subs: Valdes, Husband, Fry, Forshaw, Fischer, Ramirez, Negredo
