The Blues head to the Metalist Stadium knowing qualification to the last 16 is secure, as is top spot in Group F.
A 2-0 win was the result when City entertained the Ukrainians at the Etihad Stadium in September, with Raheem Sterling and Kevin De Bruyne on target.
A repeat would give the Blues a 100% group stage record, while Shakhtar know a draw would be enough to seal their place in the knockout stages.
When and where
Kharkiv’s Metalist Stadium will host the fixture on Wednesday 6 December, with kick-off set for 7.45pm (GMT).
In the UK, the game is live on BT Sport ESPN, while fans around the world can find out how they can tune in via our global TV listings.
Alternatively you can download our City Matchday app for Android | City Matchday app for iOs to follow the game live and we’ll also have live updates on Twitter.
Team news
City: Benjamin Mendy and John Stones remained sidelined, while De Bruyne misses the game through suspension and David Silva is not fully fit.
The young quartet of Tosin Adarabioyo, Brahim Diaz, Phil Foden and Full squad list.
Shakhtar Donetsk: Taison and Bhodan Butko are recovering from injuries, but it is yet to be confirmed whether Paulo Fonseca will be able to call upon their services.
Referee
Frenchman Benoît Bastien will be the man in the middle. He has issued 58 yellow and two red cards in his 12 Ligue One games this season.
The last time
A long range De Bruyne strike opened the scoring at the Etihad, before Sterling added a second late on to guarantee all three points.
A close first-half encounter saw the two sides go in level at the break after the visitors had looked threatening.
But Pep Guardiola’s half-time team talk did the trick and on another day, City’s second half performance would have produced a greater winning margin.
Guardiola provides Silva update
The latest team news from Ukraine ahead of City’s clash with Shakhtar
