The next stage of the defence of our trophy will come at Kenilworth Road against Rob Edwards’ team.
It represents our second trip to Luton this season after a 2-1 win in December.
Watch: City’s 2023 FA Cup journey
We reached the last 16 with a third round 5-0 thrashing of Huddersfield Town before a 1-0 victory at Tottenham Hotspur on Friday night.
Our opponents needed a replay to beat League One Bolton Wanderers in the third round and then won 2-1 at Everton to reach this stage.
Last year’s success was the seventh FA Cup triumph in our history and the second under Pep Guardiola.
Our fifth round tie will be played during the week commencing Monday 26 February.
The exact fixture date and time will be confirmed in due course on mancity.com and our official app.
Full draw details
Blackburn Rovers v Newcastle United
Chelsea or Aston Villa v Leeds United or Plymouth Argyle
AFC Bournemouth v Leicester City
Liverpool v Watford or Southampton
Bristol City or Nottingham Forest v Manchester United
Wolves v Brighton & Hove Albion
Sheffield Wednesday or Coventry City v Maidstone United
Luton Town v Manchester City
