Kick-off is set for 15:00 (UK) with Pep Guardiola’s men looking to once again create history, should we emerge as winners.
Fresh from becoming the first side in English football history to win four successive men’s top flight titles, City could also break new ground by securing back-to-back doubles, a feat that no other side has been able to emulate.
Standing in our way are a United side who ended the Premier League season with back-to-back league victories, finishing in eighth place.
Saturday’s clash is a rerun of last year’s Wembley showpiece, with an Ilkay Gundogan brace earning City a 2-1 win in the first-ever Manchester derby FA Cup final.
As always, our official app is the best place to stay on top of all the action across the day from one handy place.
Our Matchday Centre, providing detailed text commentary, stats and analysis gets under way from 13:00 and continues right through until all the post-match reaction.
Meanwhile, former City strike duo Shaun Goater and Paul Dickov are in the Matchday Live studio offering their expert insight before, during and after the game at Wembley.
As well as soaking up the atmosphere at Box Park Wembley with FG, the show will offer its typical blend of City-centric analysis, anecdotes and humour to give you a unique matchday experience.
You can also get in touch with our guests by sending a WhatsApp to +447537186538.
From kick-off, Alistair Mann and Michael Brown will call the action from the commentary box, while those with push notifications turned on will also be alerted to all the key moments of the action as they unfold.
After the final whistle, a match report and reaction from both Guardiola and members of the City squad will be made available across the evening.
Highlights and a CITY+ full-match replay, meanwhile, can be accessed from 12:00 on Sunday 26 May.