City welcome Ange Postecoglou’s side to the Etihad Stadium on Sunday 3 December, with kick-off set for 16:30 (UK).
After starting the season brightly, Spurs come into the tie on the back of three successive defeats, so will be desperate to get their early title tilt back on track.
For City, meanwhile, there’s the incentive of potentially moving top of the table, should Arsenal drop points in their clash against Wolves.
The two sides served up a cracking encounter in last season’s Etihad fixture, with a second half comeback earning the hosts a 4-2 win.
As always, the official Man City app will keep you across all the action from one handy place.
Our Matchday Centre gets under way from 14:30, providing you with detailed stats, analysis and text updates across the afternoon.
Paul Robinson, Joleon Lescott and Ledley King are in the studio for our Matchday Live show, offering their expert insight and plenty of laughs along the way on each of our official channels.
From kick-off Alistair Mann will be joined by Michael Brown in the commentary box to call the action from the Etihad Stadium, while those with push notifications turned on will also be alerted to all the key moments from wherever you are in the world.
Our app coverage also continues after the game, with a detailed match report and reaction from the boss and City players available to read shortly after the final whistle.
Short highlights from the Etihad will be published at 20:15 (UK), with extended highlights and a full-match replay (via CITY+) can be accessed from midnight (UK).