Pep Guardiola‘s men travel to St Mary’s Stadium on Wednesday 11 January, with kick-off scheduled for 20:00 (UK).
Victory would see us reach the last four of a competition that we have won four times in the past five seasons.
City enter the tie on the back of a convincing 4-0 FA Cup third round triumph against Chelsea.
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However, we will need to be at our best once again if we are to also continue our progression in the Carabao Cup.
Southampton currently sit at the foot of the Premier League but will be desperate to claim their first win under new boss Nathan Jones when Guardiola‘s men travel south.
It promises to be an exciting encounter, and the squad finalised preparations at the City Football Academy.
Check out the best images from the session below...