We face Antonio Conte’s team at the Tottenham Hotspur Stadium today, kick-off 16:30 (UK time).
Ederson returns as the goalkeeper with Kyle Walker back to the captain the side.
Bernardo Silva and Julian Alvarez return to the line-up while January signing Maximo Perrone is on the bench.
TEAMS
SPURS XI: Lloris, Emerson, Romero, Dier, Davies, Perisic, Hojbjerg, Bentancur, Kulusevski, Kane, Son.
Subs: Forster, Skipp, Sanchez, Richarlison, Danjuma, Sessegnon, Porro, Lenglet, Bissouma.
CITY XI: Ederson, Lewis, Walker (c), Akanji, Ake, Rodrigo, Bernardo, Mahrez, Grealish, Alvarez, Haaland
Subs: Ortega, Dias, Phillips, Gundogan, Laporte, De Bruyne, Gomez, Perrone, Palmer.
TACTICS
The teamsheet is through but the starting line-up could be a surprise as it offers plenty of flexibility for Guardiola in where people will start.
It looks on paper like it could be a 4-4-2 with Erling Haaland and Alvarez starting together as a strike partnership with Jack Grealish and Riyad Mahrez as wide players either side of Bernardo and Rodrigo.
At right-back, the City boss has the choice between Rico Lewis and Walker, with the possibility that the latter could step into the centre of defence alongside Manuel Akanji with Nathan Ake as the left-back.
GOAL POWER
Guardiola has opted to unleash his double strike partnership of Premier League leading scorer Haaland and World Cup winner Alvarez.
Incredibly, we have never scored at the Tottenham Hotspur Stadium so it will be vital to have as much goal threat as possible.
They both started the 4-2 victory over Spurs at the Etihad Stadium in January and were both on target to turn around a two-goal deficit before Mahrez struck twice.
NEW SIGNING
One new face in the squad is 20-year-old Argentinian midfielder Perrone.
He joined in January from Velez Sarsfield after playing 33 times for the Club.
Perrone joined up with the squad after playing at the U-20 South American Championship in Colombia.
Despite his young ages, he was a key figure at Sarsfield on their way to to the semi-finals of the Copa Libertadores.