The 20-year-old spent the latter half of the previous campaign at Stoke City, where he became an ever-present as the Potters finished 14th in the Championship.
Harwood-Bellis reunites with former City team-mate Vincent Kompany at Turf Moor, who was confirmed as Clarets manager last month.
The pair also previously worked together during the young defender’s time on loan at Anderlecht last season, which saw him feature 19 times under Kompany’s watchful eye.
Burnley are hoping for an immediate return to the top flight following relegation on the final day of the Premier League season.
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After spending the first half of the 2021/22 campaign in Belgium, Harwood-Bellis made a further 23 appearances for Stoke.
The highly rated youngster has made eight senior appearances for Pep Guardiola’s men to date after making his senior debut for City in September 2019.
His progress through the ranks was rewarded with a four-year contract in December 2020, with another successful loan move to Blackburn Rovers following soon after.
A regular for England’s Under-21s alongside fellow youngsters James Trafford, Tommy Doyle, James McAtee and Cole Palmer, the 20-year-old was also part of City’s 2020 FA Youth Cup-winning side.
Everyone at Manchester City wishes Taylor the best of luck during his spell at Burnley.