Pep Guardiola’s side travel to the Tottenham Hotspur Stadium with kick-off scheduled for 20:00 (UK) on Friday 26 January.
The fourth round fixture is the first time the two teams have met since 2003/04 when City came from 3-0 down at half-time – and with 10 men – to win 4-3 courtesy of a 90th minute winner from Jon Macken.
Barry-Murphy, the Elite Development Squad head coach, and Brown, a former City midfielder, will join host Natalie Pike in the studio from 19:00 (UK), as the team news comes in.
CITY+ | SUBSCRIBE TO ACCESS EXCLUSIVE CONTENT
Meanwhile, FG and Shaun Wright-Phillips will be pitchside in London to add their City-centric insight before, during and after the game.
We will also have our regular live audio commentary offering with Alistair Mann and Andy Morrison on hand to guide you through proceedings while our text commentary continues on the Matchday Centre.
Highlights of the match will be available from midday Saturday with the full-match replay, via CITY+, available from midnight.
Don’t forget, the best way to follow Manchester City is by downloading the official app!
And when you do, turn on notifications to get alerted as to when our Matchday Live show starts as well as all the key moments during the game.
Download on your mobile phone or tablet via Apple’s App Store or Google Play Store, or if you already have the app, the simply visit the respective store and update.