We make the short trip to city rivals Manchester United for a 16:30 (UK) kick-off.
City go into the game looking to return to winning ways after back-to-back defeats against Arsenal and Brighton.
Manchester derby | Match preview
That has left us in sixth place with 10 points from six matches.
United meanwhile have 12 points after three wins and three draws so far.
This will be the first women’s Manchester derby to be played at Old Trafford, with matches in previous campaigns taking place at Leigh Sports Village.
City hosted United at the Etihad in the reverse fixture last season, playing out a 1-1 draw in front of 44,259 fans.
As always, the official Manchester City app provides you with comprehensive coverage of our WSL clash at Old Trafford.
Our Matchday Centre will get under way from 15:00, providing detailed text commentary, stats and analysis across the afternoon.
Ahead of kick-off presenter Ellen Ellard will be joined by former City defender Onuoha pitchside to discuss the latest clash between the sides.
Nick Walsh will then be on hand to guide you through the action with live audio commentary, while those with notifications turned on will also be alerted to all the key moments as they unfold.
A detailed match report, plus reaction from Gareth Taylor can also be accessed soon after the final whistle, while highlights and a CITY+ full-match replay are available from 12:00 on Monday 20 November.