Ben Wilkinson’s youngsters welcome Spurs to the Joie Stadium on Saturday 24 February, with kick-off scheduled for 12:00 (UK).
City made it through to this stage of the competition after seeing off Reading 2-1 in the fifth round, West Ham 2-0 in the fourth round and Watford 2-0 in the third round.
Spurs, meanwhile, defeated Bournemouth 6-2 in the fifth round, Burton Albion 3-1 in the fourth round and Brentford 5-1 in the third round.
Millwall are already through to the semi-finals after beating Chelsea on penalties while the other last-eight ties include Leeds v Liverpool and Brighton City v Swindon.
CITY V TOTTENHAM | WATCH LIVE ON CITY+
City have won the FA Youth Cup three times and been runners-up eight times.
We emerged victorious in 1986, 2008 and 2020 as we now look to add 2024 to our list.
CITY+ subscribers can watch the action unfold live on mancity.com and our official app with the stream starting shortly before 12:00 (UK).
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