The trio have been back in training after all three have forced to miss our most recent games through injury.
City travel to London for our fourth round clash at the Gaughan Group Stadium on Saturday, 8 January at 12:30 (UK) and the boss says he has not decided on his starting line-up with the possibility that Dias, Ake and Doku could all come into contention.
“Maybe some of them, we will see,” Guardiola said in his prematch news conference ahead of the fourth round tie.
After a campaign disrupted by injuries, Guardiola will have a number of extra options for the clash with the League One side.
January signings Omar Marmoush, Abdukodir Khusanov and Vitor Reis could also be in his plans for the game.
And our fourth signing of the window Nico could also make his debut after completing his move from Porto earlier this week.
The boss is delighted to have the midfielder in the squad and says he is an exciting addition for the years to come at City.
“It’s a position that we were weak since the absence of Rodri,” Guardiola added.
“He’s a young player, 23 years-old and can play six or eight.
“He has physicality. He’s a strong boy. I know him from Barcelona and his father was working here.
“I’m really pleased for the club and looking ahead to the next years.”
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Our visit to Orient will be our first since the 1965/66 season with Guardiola already facing some difficult games against lower league teams in his nine seasons at the club.
The O’s were on an 11-game unbeaten streak before defeat last weekend and Richie Wellens’ side are in the promotion play-off positions.
Guardiola won’t take them lightly and is expecting a tough test against a side desperate to pull off an upset.
“Always we have problems away in this competition in the FA Cup or Carabao Cup against teams from the Championship, League One, League Two we struggle,” he added.
“Every game is an opportunity.”
