Sane was injured in the 2-0 FA Cup win at Cardiff last month.
Delph hasn’t played for several weeks and the potential return of all three will give Pep Guardiola a huge boost as City look to progress in three cup competitions in the next fortnight.
With FA Cup and Carabao Cup matches next up for the Blues, the City boss will be looking to use all the resources available for this crucial part of the campaign.
Benjamin Mendy are both making good progress from their injuries.
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The squad fly out to Switzerland later today for the first leg of the Champions League Round of 16 with FC Basel.
Then, next Monday thoughts turn to the FA Cup with a last 16 tie against Wigan Athletic at the DW Stadium before the Carabao Cup final against Arsenal a week on Sunday.
The Blues don’t return to Premier League action until 1 March with another trip to London to face Arsenal, this time at the Emirates Stadium.